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RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS
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DeCS
Descriptor
English
:
Rho Guanine Nucleotide Exchange Factors
Descriptor
Spanish
:
Factores de Intercambio de Guanina Nucleótido Rho
Descriptor
Portuguese
:
Fatores de Troca de Nucleotídeo Guanina Rho
Tree Number:
D12.644.360.325.300.099
D12.776.402.300.099
D12.776.476.325.300.099
Definition
English
:
Signaling
proteins
which function as master molecular switches by activating Rho GTPases through conversion of
guanine nucleotides
. Rho GTPases in turn
control
many aspects of cell
behavior
through the regulation of multiple downstream
signal transduction
pathways.
History Note
English
:
2014
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55310
Unique Identifier:
D064067
Occurrence in VHL
:
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